I have a facebook group Alzheimer's: Late and Early Onset, APOE4
Prior
Studies:
·
In 2005 Andrasi, et al. measured aluminum
levels in specific brain regions (e.g. hippocampus, entorhinal cortex, and two
areas of the frontal cortex) of
·
In 2011 Russina, et al, measured both aluminum
and mercury in the brains of
·
In 2017 Exley, et al. measured aluminum in the
brains of
These three studies involved measuring aluminum in a total of only
43 brains of people diagnosed with AD. Scientists who were still doubtful that
the
New
Study:
A new study was published in 2018 by McLachlan, et al., of
What is perhaps most interesting about McLachlan’s paper is the
author’s ambivalence toward aluminum chelation therapy for removing aluminum
from the brains of those with AD.
This ambivalence toward chelation therapy evidently is due to the
authors being unaware of the work published in 2006 by Exley, et al., who
References
1. Andrasi,
E., et al.; Brain Al, Mg, and P contents and Alzheimer-diseased patients; J.
Alzheimer’s Dis.; 7:273-84 (2005)
2. Fjell,
A.M., et al.; One-year brain atrophy evident in healthy aging; J. Neurosci.;
Dec.; 29(48):15223-31 (2009)
3. Rusina,
R., et al.; Higher aluminum concentrations in Alzheimer’s disease after Box-Cox
data transformation; Neurotox. Res.; 20, 329-33 (2011)
4. Mirza,
A., et al.; Aluminum in brain tissue in familial Alzheimer’s disease; J. Trace
Elements in Medicine and Biology; Mar.; 40:30-36 (2017)
5. McLachlan,
D.R.C., et al.; Aluminum in neurological disease – a 36 year multicenter study;
J. Alzheimer’s Dis. Parkinsonism; 8: 457 (2018)
6. McLachlan,
D.R.C.; et al.; Intramuscular desferrioxamine in patients with Alzheimer’s
disease; The Lancet; 337(8753):1304-8 (1991)
7. Exley,
C., et al.; Non-invasive therapy to reduce the body burden of aluminum in
Alzheimer’s
8. Davenward,
S., et al.; Silicon-rich mineral water as a non-invasive test of the ‘aluminum
hypothesis’ in Alzheimer’s disease; J. Alzheimer’s Dis.; 33(2):423-30 (2013)
9. Belles,
M., et al.; Silicon reduces aluminum accumulation in rats: Relevance to the
aluminum hypothesis of Alzheimer’s disease; Alzheimer’s Dis. Assoc. Disorders;
12(2):83-7 (1998)
